2025/2026 ADVANCED PATHOPHYSIOLOGY UTMB 5355 EXAM 2 ACTUAL Q&A 100% PASS | MODULE 4 CANCER & HEMATOLOGY

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2025/2026 ADVANCED PATHOPHYSIOLOGY UTMB 5355 EXAM 2 ACTUAL Q&A 100% PASS | MODULE 4 CANCER & HEMATOLOGY Oncogenes - Answer -cancer causing genes, promote uncontrolled growth of cells Proto-oncogenes - Answer -promote normal cell growth factor and division If proto-oncogenes are mutated the become - Answer -Oncogenes Tumor Supressor Genes (TSGs) are - Answer -Antioncogenes antioncogenes - Answer -inhibit tumor progression & prevent mutations Cancer develops with increase in - and decrease in - Answer -oncogenes, tumor suppressor genes What are the 2 main types of Tumor Suppressor Genes? - Answer -Gatekeepers & Caretakers tumor suppressor genes - Answer -encode proteins that inhibit growth, prevent and repair mutations but if mutated will increase cancer risk Need assistance on Online classes, Exams & Assignments? Reach out for instant help!! Full Course Assistance, Plagiarism-free Essay Writing, Research Paper, Dissertation, Discussion Posts, etc…. Confidential & Secure services. Tutors are available for all subjects! Email now at: tutorjean01@gmail.com Gatekeeper - Answer -regulate cell proliferation, cell type specific, normally prevent uncontrolled growth and potential progression of cancer Caretaker - Answer -suppress gene mutations, repair DNA, if not functioning correctly mutation can occur How does chronic inflammation cause cancer? - Answer -Inflammation increases free radicals and reactive oxygen species which promote mutation interfere with insulin signaling leading to insulin resistance in stress, obesity, and Type 2 Diabetes. - Answer -Pro-inflammatory cytokines TP53 gene - Answer -tumor suppressor gene, if lost due to mutation cells escape apoptosis and can divide indefinitely increasing risk of cancer tumor necrosis factor is _ cytokine - Answer -pro-inflammatory, may be related to carcinogenesis 4 functions of TNF - Answer -1)cell survival 2)cell proliferation 3) cell differentiation 4)cell death CA therapy in relation to TNF - Answer -Modulation of TNF/receptors tumor markers - Answer -not used to diagnose, but can be useful in surveillance of cancers or after cancer treatments, elevated in some cancers tumor markers are produced by both - Answer -benign & malignant cells, increased levels seen in cancerous/noncancerous tumors Need assistance on Online classes, Exams & Assignments? Reach out for instant help!! Full Course Assistance, Plagiarism-free Essay Writing, Research Paper, Dissertation, Discussion Posts, etc…. Confidential & Secure services. Tutors are available for all subjects! Email now at: tutorjean01@gmail.com